I'm actually trying to work out the methodology for the tables.
To me it looks like table 2 they aggregate all data for all samples on a per subject and per period basis and report the changes (mean?)
They describe is thus: "The first analysis included repetitive measurements to evaluate the post vaccination change compared to using T0 as reference."
The table legend says : Table 2: Percentage and absolute change 1 compared to T0 as reference measured by repeated measures analysis (total samples).
Still not sure what they've really done but it seems to include all the data.
But tables 3 and 4 - I am not sure what they have done.
Table 3 description is this: "The second analysis focused on median differences between T1, T2 and T3vs.T0 according to the first semen sample of each donor on each time frame. "
So is this the median out of all the subject's first samples? That's nuts (sorry). Can't see that it's median of each subject's samples as they say it's the first sample...you can't have a median of one.
Table 4: "Last and similarly, median differences between T1, T2 and T3 vs.T0 according to sample's mean ofeach donor were investigated."
This looks like they take the mean values for each donor and then the median value of all of those?
This looks ridiculous - they have surely lost nearly all the data in tables 3 and 4 - the relevant data seems to be table 2, glossed over in the text.
I'm actually trying to work out the methodology for the tables.
To me it looks like table 2 they aggregate all data for all samples on a per subject and per period basis and report the changes (mean?)
They describe is thus: "The first analysis included repetitive measurements to evaluate the post vaccination change compared to using T0 as reference."
The table legend says : Table 2: Percentage and absolute change 1 compared to T0 as reference measured by repeated measures analysis (total samples).
Still not sure what they've really done but it seems to include all the data.
But tables 3 and 4 - I am not sure what they have done.
Table 3 description is this: "The second analysis focused on median differences between T1, T2 and T3vs.T0 according to the first semen sample of each donor on each time frame. "
So is this the median out of all the subject's first samples? That's nuts (sorry). Can't see that it's median of each subject's samples as they say it's the first sample...you can't have a median of one.
Table 4: "Last and similarly, median differences between T1, T2 and T3 vs.T0 according to sample's mean ofeach donor were investigated."
This looks like they take the mean values for each donor and then the median value of all of those?
This looks ridiculous - they have surely lost nearly all the data in tables 3 and 4 - the relevant data seems to be table 2, glossed over in the text.